Several weeks after discharge, the patient gradually began to experience restless, deep anal discomfort, approximately 10 cm from the perineal region. Colonoscopy revealed internal haemorrhoids without other rectal lesions. Neurological findings including deep tendon reflex, perineum loss of sensory and spinal cord injury, revealed no abnormalities.

The authors, including Itaru Nakamura from Tokyo Medical University Hospital, mentioned that this case fulfilled 4 essential symptoms of RLS. To date, no case of a restless anal syndrome associated with Covid-19 has been previously published, the team said This case report may reflect the associative impacts of Covid-19 on the neuropsychiatric state. The long-term outcomes of neuropsychiatric conditions should continue to be monitored, they added.

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